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W J Thompson Selected Research

sulindac sulfone (exisulind)

11/2001Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells.
5/2001Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis.
5/2001Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1.
10/2000Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.
7/2000Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.

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W J Thompson Research Topics

Disease

5Neoplasms (Cancer)
03/2021 - 07/2000
1Carcinogenesis
05/2001
1Urinary Bladder Neoplasms (Bladder Cancer)
05/2001
1Colonic Neoplasms (Colon Cancer)
05/2001
1Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
07/2000

Drug/Important Bio-Agent (IBA)

5sulindac sulfone (exisulind)IBA
11/2001 - 07/2000
3Pharmaceutical PreparationsIBA
03/2021 - 07/2000
3Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA
11/2001 - 05/2001
3Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
05/2001 - 07/2000
2beta CateninIBA
11/2001 - 07/2000
2Cyclic GMPIBA
05/2001 - 10/2000
2Phosphotransferases (Kinase)IBA
05/2001 - 10/2000
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
10/2000 - 07/2000
1Benzene (Benzole)IBA
03/2021
11,3-butadiene (divinyl)IBA
03/2021
1Environmental CarcinogensIBA
03/2021
1Formaldehyde (Formol)FDA Link
03/2021
1guanylinIBA
11/2001
1Guanylate Cyclase (Guanylyl Cyclase)IBA
11/2001
1CarcinogensIBA
05/2001
1NitrosaminesIBA
05/2001
1Antineoplastic Agents (Antineoplastics)IBA
05/2001
1Sulindac (Copal)FDA LinkGeneric
10/2000
1Protein Isoforms (Isoforms)IBA
07/2000
1GuanosineIBA
07/2000